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    STUDIA PHYSICA - Issue no. SPECIAL ISSUE / 2001  
         
  Article:   THE EVALUATION OF SOME THERMODYNAMIC PARAMETERS BY RIA METHOD.

Authors:  I.I. DOROBANTU, DELIA-IRINA CUCU.
 
       
         
  Abstract:  Intrinsic association constant characterises the binding of an antibody with a monovalent antigen or hapten. The binding forces between antibody and the respective hapten are relatively weak and consist mainly of Van der Vaals forces, electrostatic forces and hydrophobic forces. Thus, it is important to know the thermodynamic parameters as enthalpy, Gibbs energy and the entropy involved in the formation of an antigen-antibody complex in order to characterise a certain antigen-antibody complex. The present paper evaluates some of thermodynamic parameters by using RIA (radioimmunoassay) method.  
         
     
         
         
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