The STUDIA UNIVERSITATIS BABEŞ-BOLYAI issue article summary

The summary of the selected article appears at the bottom of the page. In order to get back to the contents of the issue this article belongs to you have to access the link from the title. In order to see all the articles of the archive which have as author/co-author one of the authors mentioned below, you have to access the link from the author's name.

 
       
         
    STUDIA EDUCATIO ARTIS GYMNASTICAE - Issue no. 1 / 2011  
         
  Article:   INFLUENCE OF THE ADMINISTRATION OF FLAVONOIDS AND PHYSICAL EXERCISE ON THE OXIDANT/ANTIOXIDANT BALANCE IN RATS.

Authors:  .
 
       
         
  Abstract:  Background. The study of the effects of flavonoids on aerobic exercise capacity has evidenced their favorable influence, attributed to their in vivo ergotropic, anti-fatigue and antioxidative action. Aims. To study the influence of the administration of flavonoids on the oxidant/antioxidant (O/AO) balance in rats subjected to physical exercise of various intensities. Methods. The researches were performed in 6 groups of rats (n=10 animals/group): 2 groups of sedentary controls (group 1) and exercise trained rats (group 2) and 4 groups exercise trained for 21 days and supplemented with flavonoids, without loading (group 3), with 5% loading (group 4), with 10% loading (group 5), and with 15% loading (group 6), in which the indicators .of the O/AO balance (malondialdehyde – MDA, protein carbonyls – PC, hydrogen donor capacity – HD, and total sulfhydryl groups – SH) were measured in the serum at moments T1 – day 1 and T21 – day 21. The running treadmill test was performed. Results. The rats supplemented with flavonoids and exercise trained for 21 days have a significant MDA decrease compared to initial values and to the values of all the other groups subjected to physical exercise and supplemented with flavonoids; a significant PC increase compared to initial values; a significant HD decrease compared to initial values; a significant increase in SH groups compared to initial values. The rats supplemented with flavonoids and exercise trained with loading have at 21 days a significant MDA decrease compared to initial values – groups IV and V; a significant PC increase compared to initial values – groups IV, V and VI, and a significant PC increase compared to the values of all the other exercise trained groups supplemented with flavonoids – group IV; a significant HD decrease compared to initial values – group IV, and insignificant differences in HD changes between the groups at 21 days; a significant SH increase compared to initial values and to the values of all the other groups – groups V and VI. Conclusions. Flavonoids have in vivo AO effects, determining a HD and SH increase in sedentary rats and a SH increase in rats subjected to physical exercise of various intensities.

Key words: flavonoids, physical exercise, oxidative stress, antioxidants. 

 
         
     
         
         
      Back to previous page