The STUDIA UNIVERSITATIS BABEŞ-BOLYAI issue article summary

The summary of the selected article appears at the bottom of the page. In order to get back to the contents of the issue this article belongs to you have to access the link from the title. In order to see all the articles of the archive which have as author/co-author one of the authors mentioned below, you have to access the link from the author's name.

 
       
         
    STUDIA CHEMIA - Issue no. Special Issue 2 / 2009  
         
  Article:   QUANTIFICATION OF IBUPROFEN AND PSEUDOEPHEDRINE IN HUMAN PLASMA BY LC/MS/MS FOR PHARMACOKINETIC STUDIES.

Authors:  LAURIAN VLASE, SORIN E. LEUCUŢA, FLORIN DAN IRIMIE.
 
       
         
  Abstract:  

A simple, fast and sensitive LC/MS/MS method for quantification of ibuprofen and pseudoephedrine in human plasma has been developed and validated. The lower limit of quantification was established at 0.05 μg/ml IBU and 5 ng/ml PSE. Ibuprofen and pseudoephedrine were separated under isocratic conditions on a Zorbax RX C18 column (3.0 x 100mm, 3µ).

 

Keywords: ibuprofen, pseudoephedrine, LC/MS/MS, bioequivalence

 
         
     
         
         
      Back to previous page