The STUDIA UNIVERSITATIS BABE┼×-BOLYAI issue article summary

The summary of the selected article appears at the bottom of the page. In order to get back to the contents of the issue this article belongs to you have to access the link from the title. In order to see all the articles of the archive which have as author/co-author one of the authors mentioned below, you have to access the link from the author's name.

 
       
         
    STUDIA CHEMIA - Issue no. 4, Tom I / 2017  
         
  Article:   PERIODATE-OXIDIZED ALGINATE AS POLYCONDENSATION REAGENT FOR HEMOGLOBIN.

Authors:  FLORINA SCURTU, ANAMARIA POPA, RADU SILAGHI-DUMITRESCU.
 
       
         
  Abstract:  We have previously demonstrated that derivatization of hemoglobin with periodate-modified sugar derivatives incurs increases in the pro-oxidant reactivity and, also, that serum bovine serum albumin can resolve this problem entirely. Here, we described a new polymer based on hemoglobin and another oxygen-containing compound, alginate. The rate of autooxidation increases after derivatization, but serum albumin alleviates this problem. The peroxide reactivity and oxygen affinity were also tested but no significant differences were observed between derivatized and native hemoglobin.

Keywords: blood substitute, hemoglobin, alginate, oxidative stress
 
         
     
         
         
      Back to previous page