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    STUDIA CHEMIA - Issue no. 4 / 2021  
         
  Article:   BIOACTIVE POLYPHENOLIC COMPOUNDS FROM MOTHERWORT AND HAWTHORN HYDROETHANOLIC EXTRACTS.

Authors:  ANDREEA-MIRUNA NEAGU, CORNELIU-MIRCEA CODREANU, VASILE STAICU, RALUCA STAN.
 
       
         
  Abstract:  
DOI: 10.24193/subbchem.2021.4.09

Published Online: 2021-12-30
Published Print: 2021-12-30
pp. 123-132

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Motherwort (Leonurus cardiaca) and Hawthorn (Crataegus monogyna) are known from traditional phytotherapy as being effective in alleviating many cardiovascular system disorders. This paper presents the studies made to assess the phytochemical compozition of the herbal extracts prepared from Motherwort (aerial parts), Hawthorn (fruits) and Hawthorn (flowers and leaves) by maceration, percolation and reflux using a mixture of ethanol and water as solvent. Optimum extraction conditions were evaluated for enhancing the content of the active substances (certain flavones and polyphenols: anthocyanins, etc.) present in the two studied plants, that are useful in the prevention of many cardiovascular disorders. Their chemical composition was investigated using UV-VIS spectroscopy methods: total polyphenolic content, total flavones content and the antioxidant activity were determined. The study showed that reflux extraction technique is more effective for extracting polyphenolic compounds from the two studied medicinal plants. Varying the extraction parameters led to the attainment of new phytotherapeutic extracts that are optimally beneficial in the phytotherapy of cardiovascular diseases.

Keywords: Hawthorn, Motherwort, reflux, percolation, maceration, polyphenols
 
         
     
         
         
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