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    STUDIA CHEMIA - Issue no. 3 / 2023  
         
  Article:   NANOCOMPOSITE BASED ON HYDROXYAPATITE AND SILVER WITH ANTIBACTERIAL ACTIVITY.

Authors:  AURORA MOCANU, DIANA ALEXANDRA FLOREA, GHEORGHE TOMOAIA, LUCIAN CRISTIAN POP, ANCUTA DANISTEAN, SORIN RAPUNTEAN, OSSI HOROVITZ, MARIA TOMOAIA-COTISEL.
 
       
         
  Abstract:  
DOI: 10.24193/subbchem.2023.3.01

Published Online: 2023-09-30
Published Print: 2023-09-30
pp. 7-18

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A nanocomposite made from hydroxyapatite (HAP) and silver nanoparticles (AgNPs), namely HAP-4.5 wt% AgNPs, is reported. HAP was prepared using a wet precipitation technique, and AgNPs were made by reducing silver nitrate with glucose in basic medium. HAP, AgNPs and HAP-4.5 wt% AgNPs composite were characterized by X-ray diffraction (XRD), SEM - energy dispersive X-ray spectroscopy (EDS) and different imagistic methods: TEM and AFM. The antibacterial effect of the HAP-4.5 wt% AgNPs nanocomposite was tested using diffusion technique in nutritive agar on two pathogenic species, one Gram-negative (Salmonella typhimurium) and one Gram-positive (Bacillus cereus) and promising results were obtained. This hydroxyapatite-silver nanocomposite can be employed as a potential antimicrobial coating for dental and orthopedic implants, or they can be utilized such as bone cements in clinical procedures.

Keywords: hydroxyapatite, silver nanoparticles, nanocomposite, antibacterial activity, pathogens
 
         
     
         
         
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