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    STUDIA CHEMIA - Issue no. 3 / 2011  
         
  Article:   ADSORPTION AND RELEASE STUDIES OF TETRACYCLINE FROM A BIOACTIVE GLASS.

Authors:  VIORICA SIMON, EMILIA S. VANEA, SIMONA CAVALU, FLORIN BĂNICĂ, ZSOLT BENYEY, GÜLTEKIN GÖLLER.
 
       
         
  Abstract:  This study aims to characterize a bioactive glass and to evaluate its ability to adsorb and release antimicrobial agents like tetracycline. Tetracycline adsorption and release were investigated using Fourier transform infrared spectroscopy, X-ray photoelectron spectroscopy and scanning electron microscopy. The amounts of withdrawn solution, after drug release, were analyzed by differential pulsed voltammetry and UV-Vis spectroscopy. The investigated glass system promotes an efficient response concerning the tetracycline loading and release in terms of drug delivery system for biomedical applications.

Keywords: tetracycline, XPS, SEM, FTIR, UV-vis, bioactive glass
 
         
     
         
         
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