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    STUDIA CHEMIA - Issue no. 1 / 2014  
         
  Article:   PSEUDOMONAS FLUORESCENS LIPASE AS BIOCATALYST IN THE ENZYMATIC KINETIC RESOLUTION OF CHIRAL PHENOTHIAZIN ETHANOLS.

Authors:  .
 
       
         
  Abstract:   The synthesis of both enantiomers of 1-(10-ethyl-10H-phenothiazin-2-yl)-1-ethanol by enzymatic kinetic resolution of the racemic alcohol or his corresponding acetate was performed using lipase from Pseudomonas fluorescens (PFL) as biocatalyst. PFL was next immobilized by sol-gel encapsulation. The stability, activity and reusability of the obtained enzyme preparations were also determined.

Keywords: enzymatic kinetic resolution, lipase from Pseudomonas
 
         
     
         
         
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