The STUDIA UNIVERSITATIS BABEŞ-BOLYAI issue article summary

The summary of the selected article appears at the bottom of the page. In order to get back to the contents of the issue this article belongs to you have to access the link from the title. In order to see all the articles of the archive which have as author/co-author one of the authors mentioned below, you have to access the link from the author's name.

 
       
         
    STUDIA BIOLOGIA - Issue no. 1 / 2022  
         
  Article:   REVEALING THE CRISPR ARRAY IN BACTERIA LIVING IN OUR ORGANISM.

Authors:  MATEI-ȘTEFAN DOBRESCU, DUMITRANA IORDACHE, ANCA BUTIUC-KEUL.
 
       
         
  Abstract:  
DOI: 10.24193/subbbiol.2022.1.07

Article history: Received: 31 March 2022; Revised: 27 April 2022;
Accepted: 9 June 2022; Available online: 30 June 2022.
©2022 Studia UBB Biologia. Published by Babeş-Bolyai University.
pp. 131-142

VIEW PDF

FULL PDF

CRISPR (clustered regularly interspaced short palindromic repeats) is an immune system used by bacteria to defend themselves from different types of pathogens. It was discovered that this immune system can modify itself in specific regions called spacers due to previous interaction with foreign genetic material from phages and plasmids. Through our research, we have identified in different bacterial isolates CRISPR arrays belonging to the subtypes I-E (present in 42 samples) and I-F (present in 9 samples). The number of spacers in CRISPR arrays was also estimated based on the array length as a possible connection with the systems activity. Our results yielded arrays as small as 200 bp and as large as 1400 bp.

Keywords: CRISPR array; clinical isolates; pathogens; bacteria
 
         
     
         
         
      Back to previous page