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    STUDIA BIOLOGIA - Issue no. 1 / 2014  
         
  Article:   THE EVOLUTION OF GENDER DETECTION PROTOCOLS IN BIOARCHAEOLOGICAL STUDIES.

Authors:  CRISTINA MIRCEA, BEATRICE KELEMEN.
 
       
         
  Abstract:  VIEW PDF: THE EVOLUTION OF GENDER DETECTION PROTOCOLS IN BIOARCHAEOLOGICAL STUDIES

Accurate gender attribution has always been a priority in forensic casework and has always concerned the archeologists. Characteristics of forensic DNA samples analysis are similar to that of ancient DNA, small quantities of workable molecules being the main resemblance. The most frequently used markers for molecular sex attribution are the single copy gene for amelogenin located on X (AMELX) and Y (AMELY) chromosomes. Worldwide used sex determination kits were designed based on amelogenin genes amplification, especially useful in forensic casework. Sometimes these sex tests fail due to allelic dropout. New molecular markers for sex identification are constantly developed to overcome this problem. Another issue characteristic for ancient DNA studies is the contamination of samples with modern molecules of DNA. The accuracy of sex tests for ancient DNA studies depends on the possibility to discriminate between authentic ancient DNA and modern contaminant DNA. 

 Keywords: physical anthropology, sex attribution, molecular sex attribution, AMELX, AMELY, ancient DNA.
 
         
     
         
         
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