AMBIENTUM BIOETHICA BIOLOGIA CHEMIA DIGITALIA DRAMATICA EDUCATIO ARTIS GYMNAST. ENGINEERING EPHEMERIDES EUROPAEA GEOGRAPHIA GEOLOGIA HISTORIA HISTORIA ARTIUM INFORMATICA IURISPRUDENTIA MATHEMATICA MUSICA NEGOTIA OECONOMICA PHILOLOGIA PHILOSOPHIA PHYSICA POLITICA PSYCHOLOGIA-PAEDAGOGIA SOCIOLOGIA THEOLOGIA CATHOLICA THEOLOGIA CATHOLICA LATIN THEOLOGIA GR.-CATH. VARAD THEOLOGIA ORTHODOXA THEOLOGIA REF. TRANSYLVAN
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The STUDIA UNIVERSITATIS BABEŞ-BOLYAI issue article summary The summary of the selected article appears at the bottom of the page. In order to get back to the contents of the issue this article belongs to you have to access the link from the title. In order to see all the articles of the archive which have as author/co-author one of the authors mentioned below, you have to access the link from the author's name. |
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STUDIA PHYSICA - Issue no. 1-2 / 2017 | |||||||
Article: |
XRD CHECKING OF CRYSTALLINE FORMS RESULTED BY SLOW EVAPORATION OF 5-FLUOROURACIL SOLUTIONS OBTAINED WITH DIFFERENT SOLVENTS. Authors: C. MOISESCU-GOIA, M. MURESAN-POP, V. SIMON. |
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Abstract: The present study aimed to obtain new crystalline forms of 5-fluorouracil (5-FU) chemotherapy drug after 5-FU solvation in different solvents, considering the crystallization by slow evaporation. The expectation was to obtain 5-FU polymorphs. 5-FU was tested in aqueous solutions of 14 solvents. After slow evaporation of solutions (11) or suspensions (3), the obtained crystalline forms were examined by checking their X-ray diffraction patterns. Only for acetonitrile solution resulted a polymorph of 5-FU. Key words: 5-fluorouracil; solubility; X-ray diffraction; polymorphs.
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