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    STUDIA EDUCATIO%20ARTIS%20GYMNASTICAE - Issue no. 3 / 2011  
         
  Article:   THE INFLUENCE OF ANTEPARTUM HYPOBARIC HYPOXIA ON THE MOTOR AND EMOTIONAL BEHAVIOR IN DESCENDING RATS.

Authors:  . 		 
       
         
  Abstract:  Background. Hypobaric hypoxia was used by many authors as an experimental model for reproducing ADHD in rodents. Aims. The motor and emotional behavior were studied on male and female rats, descendants from pregnant females exposed to hypobaric hypoxia (Hh). Matherials and methods. The sudy was made on 4 groups of males and females rats descendants from pregnant control females and from pregnant females exposed to hypoxia; hypoxia 12% 14 days long, before birth (23 h/d). The used tests were Elevated Plus Maze and Open Field Test. The studied moments were T21, T42, T 90 – days after birth coresponding to human age: childhood, puberty, adult. Results: Antepartum Hh induces changes of the spontaneous behavior (movements, rearings) and of the emotivity (micturitions, defecations and the time spent in open filed) at the male and female descending rats.Conclusions: Antepartum Hh induces ADHD like behavior at the male descendings with hyperkinesia, hiperemotivity and hypoanxiety.

Keywords: hypobaric hypoxia, Elevated Plus Maze, Open Field Test, spontaneous motility, emotivity, anxiety, rats 		 
         
     
         
         
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