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    STUDIA CHEMIA - Issue no. 4(I) / 2009  
         
  Article:   NEW WAYS FOR OLD STRUCTURES.

Authors:  FLORIN DAN IRIMIE, CSABA PAIZS, MONICA TOŞA, PAULA PODEA. 		 
       
         
  Abstract:  Classical heterocyclic structures of furan, benzofuran, dibenzofuran, phenothiazine and benzothiazole type, previously synthesized and studied by Professor Fărcăşan, were derivatized using cell- or enzyme-assisted regio-, chemo- and stereoselective techniques, providing compounds extremely difficult or even impossible to produce by traditional chemical methods. The present report underlines the high potential of biocatalysis to perform selective enantiomer- and enantiotope-transformations with remarkable conversion rates and purities.

Keywords: heterocycles, bezofuran, (furyl)benzothiazole, regioselectivity, chemoselectivity, enantiomer-selectivity, enantiotop-selectivity
  
         
     
         
         
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