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The amperometric responses of G/CDH and Au-4-mercaptophenol/CDH modified electrodes to lactose were comparatively recorded under flow injection and cyclic voltammetry operating modes, respectively. The differences noticed between the characteristic parameters of the two investigated bioelectrodes were explained in terms of the influences exerted by the given experimental conditions on direct electron transfer process, existing between cellobiose dehydrogenase (CDH) and the investigated electrode materials.

Keywords: amperometric biosensors, cellobiose dehydrogenase, direct electron transfer, self-assembled monolayer, Au and graphite modified electrodes