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    STUDIA CHEMIA - Issue no. 2 / 2004  
         
  Article:   MODELING AND SIMULATION OF RESIDUAL PANTOLACTONE EXTRACTION FROM CALCIUM PANTOTHENATE SOLUTION.

Authors:  CĂLIN-CRISTIAN CORMOŞ, PAUL ŞERBAN AGACHI.
 
       
         
  Abstract:  In this paper the mathematical model and the simulation for the extraction process of residual pantolactone from racemic calcium pantothenate solution have been described. The aqueous solution of calcium pantothenate resulted from synthesis process contains residual racemic pantolactone that is extracted using dichloromethane. The pantolactone extraction process can be done in two technological ways. The first possibility is to use an extraction system consisting of a reactor and a packed extraction column, operated batchwise. The second possibility is to use a continuous counter-current centrifugal extractor. In this second way, economy of time, extraction solvent and energy savings are achieved. The mathematical models of the extraction process were simulated using ChemCAD 5.0 software package. From the simulation results very valuable information can be obtained regarding real plant operation.  
         
     
         
         
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