AMBIENTUM BIOETHICA BIOLOGIA CHEMIA DIGITALIA DRAMATICA EDUCATIO ARTIS GYMNAST. ENGINEERING EPHEMERIDES EUROPAEA GEOGRAPHIA GEOLOGIA HISTORIA HISTORIA ARTIUM INFORMATICA IURISPRUDENTIA MATHEMATICA MUSICA NEGOTIA OECONOMICA PHILOLOGIA PHILOSOPHIA PHYSICA POLITICA PSYCHOLOGIA-PAEDAGOGIA SOCIOLOGIA THEOLOGIA CATHOLICA THEOLOGIA CATHOLICA LATIN THEOLOGIA GR.-CATH. VARAD THEOLOGIA ORTHODOXA THEOLOGIA REF. TRANSYLVAN
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Authors: CECILIA CHIRIAC, ANDRA-SORINA TĂTAR, CLAUDIA RADU, IULIA LUPAN, BEATRICE KELEMEN.
Tuberculosis is today one of the most spread infectious human diseases, being caused by a group of closely related species included in the Mycobacterium tuberculosis complex (MTBC). Molecular studies targeting tuberculosis affected human remains are important in order to understand the evolution of specific genomic sites related to virulence. The aim of this review is to describe several techniques that are useful for the confirmation of pathogen persistence in the human archaeological remains. It also presents the genomic loci investigated in the field of molecular bioarchaeology for discrimination of MTBC species.
Keywords: tuberculosis, FT-IR, MALDI-TOF-MS, HPLC, ancient-DNA
